Effect of concentrated growth factor on random pattern skin flap viability: experimental study
نویسندگان
چکیده
منابع مشابه
Effects of insulin-like growth factor-1 on random pattern skin flap survival in rats.
PURPOSE To investigate the effects of pharmacological delay with insulin-like growth factor-1 (IGF-1) on skin flap survival. METHODS Thirty Sprague-Dawley rats were submitted to dorsal skin flap (3x9 cm). Seven days before the surgery, the animals were subdivided into three groups of 10 rats. In group 1 (controls), no injection was done. Seven days before the elevation, saline had been inject...
متن کاملPrevention of unfavourable effects of cigarette smoke on flap viability using botulinum toxin in random pattern flaps: An experimental study.
BACKGROUND There are numerous clinical and experimental studies reporting unfavourable effects of cigarette smoke on skin flaps. OBJECTIVE To investigate whether unfavourable effects of cigarette smoke on flap survival could be reduced by botulinum toxin type A. METHODS Twenty-eight male Wistar albino rats (15 months of age, mean weight 210 g [range 180 g to 230 g]) were included. They were...
متن کاملThe Effect of Enoxaparin and Clopidogrel on Survival of Random Skin Flap in Rat Animal Model
BACKGROUND Necrosis of skin flaps is considered as an important complication in reconstructive surgery. We conducted an experimental study to investigate the efficacy of low-molecular weight heparin, clopidogrel and their combination to improve the flap survival. METHODS Forty male, adult Sprague-Dawlay rats were divided randomly into 4 groups. Standard rectangular, distally based dorsal ran...
متن کاملViability of a random pattern dorsal skin flap, in diabetic rats.
PURPOSE Evaluation of the viability of a random pattern dorsal skin flap, in rats with experimentally induced diabetes mellitus. METHODS Thirty adult, male, Wistar EPM rats were distributed, at random, in two groups: I--Control (flap elevation) and II--Experimental (flap elevation ten days after alloxan induced diabetes). RESULTS The mean areas of necrosis in the different groups were 36.4%...
متن کاملOral administration of alanyl-glutamine and glutamine improve random pattern dorsal skin flap survival in rats
Objective(s): Skin flap necrosis is the most common postoperative side effect in reconstructive surgeries. Glutamine (GLN) has been shown to accelerate wound healing process. The purpose of this study was to evaluate the effects of GLN either in free form or in the dipeptide form along with L- alanyl (Ala-GLN) on random skin flaps survival in rats.Materials and Methods: Dorsal skin flaps with c...
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ژورنال
عنوان ژورنال: Journal of Health Sciences and Medicine
سال: 2020
ISSN: 2636-8579
DOI: 10.32322/jhsm.680345